Protein Info for GFF3773 in Variovorax sp. SCN45

Annotation: Fatty acid hydroxylase family (carotene hydroxylase/sterol desaturase)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 43 to 62 (20 residues), see Phobius details amino acids 89 to 111 (23 residues), see Phobius details amino acids 123 to 142 (20 residues), see Phobius details amino acids 189 to 213 (25 residues), see Phobius details PF04116: FA_hydroxylase" amino acids 128 to 262 (135 residues), 105.4 bits, see alignment E=1.6e-34

Best Hits

KEGG orthology group: None (inferred from 61% identity to ara:Arad_3394)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>GFF3773 Fatty acid hydroxylase family (carotene hydroxylase/sterol desaturase) (Variovorax sp. SCN45)
MTRPPREARSRLRAVLPWLMWPALYGAGLLGAGAAFASDAPLPWFNTVYLSLALAIAACE
RWMPHEPRWLANDGETPCNLAHTLLTKGFAQVVAALVASAPLAAATAVAAARNAGGPWPS
HWPLPAQVVLALLVAELGLYIAHRSAHHLPLLWRFHALHHSVRRLWVLNTGRFHFIDSAF
KALLGQLPLYLLGAPLAVFMWVGAVTAVTGLLTHCNIEMRTGWLDRVFSTPALHRWHHSK
LLAEGNRNYGENLVLWDQLFGTWFNPPRRPPADIGIHGQVAPRFLAQLAQPFTASGVRQI
MGMPPVRRHNGPTSSAPEAGEPIRKT