Protein Info for PS417_19310 in Pseudomonas simiae WCS417

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 387 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 44 to 60 (17 residues), see Phobius details amino acids 72 to 90 (19 residues), see Phobius details amino acids 96 to 121 (26 residues), see Phobius details amino acids 133 to 152 (20 residues), see Phobius details amino acids 159 to 178 (20 residues), see Phobius details amino acids 199 to 218 (20 residues), see Phobius details amino acids 237 to 257 (21 residues), see Phobius details amino acids 269 to 287 (19 residues), see Phobius details amino acids 290 to 316 (27 residues), see Phobius details amino acids 329 to 349 (21 residues), see Phobius details amino acids 357 to 378 (22 residues), see Phobius details PF12832: MFS_1_like" amino acids 7 to 361 (355 residues), 372.3 bits, see alignment E=4.3e-115 PF03825: Nuc_H_symport" amino acids 9 to 356 (348 residues), 62.4 bits, see alignment E=6.4e-21 PF07690: MFS_1" amino acids 13 to 247 (235 residues), 50.3 bits, see alignment E=2.7e-17 amino acids 210 to 375 (166 residues), 56.6 bits, see alignment E=3.3e-19

Best Hits

KEGG orthology group: K05820, MFS transporter, PPP family, 3-phenylpropionic acid transporter (inferred from 97% identity to pfs:PFLU4337)

Predicted SEED Role

"Nucleoside:H+ symporter:Major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U1R0 at UniProt or InterPro

Protein Sequence (387 amino acids)

>PS417_19310 MFS transporter (Pseudomonas simiae WCS417)
MTPALPYWRLSSFYLFYFALLGATAPFLALYFDHLGFSSARIGELVAIPMLMRCVAPNLW
GWLGDYTGRRLAIVRFGAVCTLASFSLIFISHTYAWLALVMALHAFFWHAVLPQFEVITL
AHLQKQTSRYSQIRLWGSIGFILTVVIMGRLFDWLSLDIYPVVVVVIMAGIIGASVWVPN
AQPASHGNRLAGEGFLKQLRSPGVLAFYACVALMQMSHGPYYTFLTLHLEHLGYSRGVIG
MLWALGVVAEVLMFLAMSRILSRFSVRRVLLASFLLAALRWLLLGSFAEFFWVLLLAQVM
HAATFGSFHAAAIAFVQRSFGDRQQGQGQALYAALAGTGGALGALYSGYSWNLLGPTLTF
SIASVAALAAAVIIGFRLQEQNQGTLQ