Protein Info for GFF3769 in Sphingobium sp. HT1-2

Annotation: Putative cytochrome P450 hydroxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 442 PF00067: p450" amino acids 232 to 398 (167 residues), 80 bits, see alignment E=8.3e-27

Best Hits

Predicted SEED Role

"putative cytochrome P450 hydroxylase" in subsystem Nitric oxide synthase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

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Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (442 amino acids)

>GFF3769 Putative cytochrome P450 hydroxylase (Sphingobium sp. HT1-2)
MRDYSTADFYKDVDLVDDPHAYFDFLRAQGPVTRLPHRNVVAVTGYEETVQVMLDTEHFS
SINAVTGPMTDLPFTPQGDDIAAELEAARPKIAFADQIVTESGTRHAKLRSVIGSLFTPS
RLKALEPSLYATADSLIDEFAADGKVDLVRQYGGPYATLVIADLLGIPAKGRAAFRVLLE
GAVPAQIDGSPEDLKHNPLVGLGKHMFRYIAWRRFLNHPAVLPVRRLLGADTEKKDILTT
LALAKFPDGTNPTLVDLTAMAAFLFGAGQDTTNRLLANAFRIIAIRPDIQAQLRADPKRI
PNFLEEVLRYDGSVKSGGRICTRTTELGGVEIKAGTTILMSHMAANRDPRRFDNPAQFDM
DRPRAKEHLAFGRGAHTCIGAPLARREVAVSIERLLARMGNIRLSPAHHGAGEALRFDYE
PTYILRALRHLHLEFDPIADPG