Protein Info for GFF3768 in Sphingobium sp. HT1-2

Annotation: O-antigen acetylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 617 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 35 to 55 (21 residues), see Phobius details amino acids 76 to 96 (21 residues), see Phobius details amino acids 146 to 163 (18 residues), see Phobius details amino acids 168 to 185 (18 residues), see Phobius details amino acids 191 to 214 (24 residues), see Phobius details amino acids 224 to 241 (18 residues), see Phobius details amino acids 247 to 264 (18 residues), see Phobius details amino acids 275 to 295 (21 residues), see Phobius details amino acids 307 to 329 (23 residues), see Phobius details amino acids 350 to 371 (22 residues), see Phobius details PF01757: Acyl_transf_3" amino acids 10 to 327 (318 residues), 102.5 bits, see alignment E=2.5e-33 PF19040: SGNH" amino acids 396 to 614 (219 residues), 184 bits, see alignment E=4.1e-58

Best Hits

KEGG orthology group: None (inferred from 62% identity to swi:Swit_4615)

Predicted SEED Role

"O-antigen acetylase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (617 amino acids)

>GFF3768 O-antigen acetylase (Sphingobium sp. HT1-2)
MIGAGRYRRDIDGLRAIAILPVLFFHAHIPGFSGGYVGVDIFFVISGFLITGIIAREVDE
QRFSLVHFYERRFRRIMPALSLMILAVLAAACWLYLPGDIEGVPKSALAATLFASNLWFF
TDTGYFAGGADVKPLLHTWSLAVEEQYYLGFPILLMLVARFAARWRGLIVGAIAALSLAL
AIALQRDTSGFTFYLLPTRAWELFAGALLALGAIPAARQRWLREALAWSGLLSVTFAVIF
YTRETVFPGITALPPVLGAALLLHSAPGTSVGRLLSLRLFVGVGLISYSLYLWHWPLIVF
TEYATDAALTGSTAIAVVTASFIAAILSWRFVERPFRDARRIPARRIFQFTGGAMALLCL
LSLALLAMGGWPQRFAPQVLQLAAGRTDISPTRKACHDTFARGAQPCILGAKVRPDALLW
GDSHGVEMAYALSLRARAEGRALIERTTSSCPPVLGYDAPKDARCARANQAALAAIRADP
AIRRIYLAAFWANGEFDDPAFVAKLDTTIHALRAEGRQVILIGPVPPQPFDVPRHLAHLA
RAGDLAQAQGVDRATIEARTRNLRALFARWQARGVTLIDPMARLCDARRCTIIHDGKPLY
FDSHHLSVAGARLVIGE