Protein Info for PS417_19185 in Pseudomonas simiae WCS417

Annotation: toxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 997 TIGR03696: RHS repeat-associated core domain" amino acids 587 to 667 (81 residues), 87.3 bits, see alignment E=3.9e-29

Best Hits

Predicted SEED Role

"Putative insecticidal toxin complex" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U6I3 at UniProt or InterPro

Protein Sequence (997 amino acids)

>PS417_19185 toxin (Pseudomonas simiae WCS417)
MPISLHRNTPSLTAFDPRGLIVRNVEYHRSSAQSEPQVRIHRQVFDSSGLMIEQWDPRLL
QLSHSEAGTRANQRTVYSLGGNALRIDSVDAGWRLTLPGEAGQLLEEWDGRGAHQAHHYD
QYVRPIAVFEQAANDEQPLCVERIAYASHSLEEAAHNRCGRVIRHDDGGGSLFHELYGLH
GEVVRQTRRFRQATAALDWPLDDAQRDARLEPEHFQASTGFSALGERLHHTDAKGNRLEY
AYGIDGQPASIVVLPTGGVRTPLMGQRRYNAAGRVISERAGNGVVRTLLYRETDGRLRQM
SARVQGAASTALQDLTYDYDCVGNIVRIDDLAQPTQWSSNTRISSACVYEYDTLSQLTKA
SGRETAGNQGGPALPARLEFGSTDDSVWRRYTQQFSYDAAGNLLELQHVPSSGTGFTRRM
SVAATSNHFMPQADGSAVSGWGQDFDRNGNLQAFEGHHGMGWDVRNQLVRITQVQREGGN
DDEERYAYDATGRRILKRRVTHAKGVSHTAQVRYLPGLEIRHDSATGEQLNVLNLDVGTL
TVRLLFWDRHPSGGSQDVQIRYGLSDHLGSSTMELGEQAQLLSQESYYPYGGTAWWAAKS
ASEASYKFIRYSGKERDASGLSYYGFRYYAPWLCRWISPDPTGDADGLNLYAMVGGNPVT
KVDEQGLTATPALEQPRQTQLRRLSISRRLAHMARIARPRMQAGASAAIRDGLSTYIANA
ISTGVDLAVFSNIQPTAQRNQILRLTVAVLDAVSTAHMSTGVAGNWTRFAPQIGALFAGA
AGVGYTVYGDSIGDQAEHSWDPVAVRRLGGHVRALSRELVQQVLRGHGTGVSWGSTPLRG
RVTRTAGATAAYGLATVANAVYGGEVPALMLPNVTPAIEAYDAAMGKMIRGGHPTATHDS
HGQTLQLPDPVATAHGGLSRMFNQVWTHWAASGVEALAVALTGSPVASQGRVTRNIVMVA
RGMISALTEWRGFFVQFARRGYSTLEAGWRRGPRPTK