Protein Info for GFF3745 in Xanthobacter sp. DMC5

Annotation: Chromosome-partitioning protein ParB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 TIGR00180: ParB/RepB/Spo0J family partition protein" amino acids 35 to 211 (177 residues), 187.1 bits, see alignment E=1.3e-59 PF02195: ParBc" amino acids 40 to 128 (89 residues), 98.4 bits, see alignment E=3.3e-32 PF17762: HTH_ParB" amino acids 179 to 226 (48 residues), 54.5 bits, see alignment 1.3e-18 PF23552: ParB_dimer" amino acids 247 to 295 (49 residues), 55 bits, see alignment 6.6e-19

Best Hits

Swiss-Prot: 52% identical to PARB_CAUVC: Chromosome-partitioning protein ParB (parB) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K03497, chromosome partitioning protein, ParB family (inferred from 79% identity to xau:Xaut_1837)

Predicted SEED Role

"Chromosome (plasmid) partitioning protein ParB" in subsystem Bacterial Cytoskeleton or Plasmid replication or Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (297 amino acids)

>GFF3745 Chromosome-partitioning protein ParB (Xanthobacter sp. DMC5)
MADEQRSRLGRGLAALIGEMGEPQAAPTRSSGTRGGPRRVPIEQVKANPRNPRRAFLEEG
LEDLTASIREKGIIQPIVVRPLKGSDSFEIVAGERRWRAAQRASLHEVPVVVLDLSDREA
LEIAIIENVQRADLNPVEEAQGYEALMDEFEYNQNELSKVIGKSRSHIANTLRLLKLPEA
VKGHLAEGRLSAGHARALLAVSDPEKVAREVIAKGLTVRDVEALSKAKTPPAPVTGRGAP
APAPERKSADTRALEKRLADALGLAVSLEGKGEAGELRIRYASLDQLDEICRKLGLD