Protein Info for GFF3741 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 516 signal peptide" amino acids 12 to 19 (8 residues), see Phobius details transmembrane" amino acids 20 to 31 (12 residues), see Phobius details amino acids 55 to 73 (19 residues), see Phobius details amino acids 85 to 102 (18 residues), see Phobius details amino acids 115 to 135 (21 residues), see Phobius details amino acids 146 to 166 (21 residues), see Phobius details amino acids 173 to 193 (21 residues), see Phobius details amino acids 209 to 227 (19 residues), see Phobius details amino acids 237 to 256 (20 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details amino acids 312 to 331 (20 residues), see Phobius details amino acids 342 to 359 (18 residues), see Phobius details amino acids 371 to 393 (23 residues), see Phobius details amino acids 410 to 429 (20 residues), see Phobius details amino acids 488 to 511 (24 residues), see Phobius details PF00083: Sugar_tr" amino acids 21 to 194 (174 residues), 41 bits, see alignment E=1.2e-14 PF07690: MFS_1" amino acids 24 to 419 (396 residues), 103 bits, see alignment E=1.6e-33

Best Hits

KEGG orthology group: None (inferred from 65% identity to brh:RBRH_03755)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (516 amino acids)

>GFF3741 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MSSPALAWPSRGNAAVALLPWAIGLVTAIDYFDNALFAFFASYIAGGVNASPDELVWASS
AYALGAVLGILHQHAWVERLGYRRYLAVCMFAFALGGVGAALCDSSMQLTAARAVQGYFV
GPMLGACRILIQIGIAPARRAQALKAFMVLIVFGGALAPIAGAFLVTNFDWRWLFACTAP
AAALIGLLVLWTLPDIGDVAPHERTEPHYIAYVVFALAQAALQVVLTRSHFELFTGSPAL
IGLTLAGVAGLAWFGWQQWRHPAPLVRLHALRNASFRVGLALYVVYYYLSTGFSYLLPRM
MEGGLGFTVGNTGYFTGAASLATGLLVFVYLKYSARLTRKKWLIVAGFGIAALAAWWLSR
VTPQAGREALLGPLLLRGLLMLFVVLPVANLTFRPFAAEEFAHGYRLKNLVRQLAISFAT
SSVIALQQHRLALHEVRLGESANPANASFMQALESLTHGFAAAGHAAGEAHAMALGTLYR
TLEQQATFMASLDGFTAMAVIALAAGVFAAWQKTID