Protein Info for GFF3736 in Variovorax sp. SCN45

Annotation: UPF0102 protein YraN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 122 TIGR00252: TIGR00252 family protein" amino acids 6 to 120 (115 residues), 81.9 bits, see alignment E=1.8e-27 PF02021: UPF0102" amino acids 14 to 108 (95 residues), 83.7 bits, see alignment E=4.9e-28

Best Hits

Swiss-Prot: 70% identical to Y630_VEREI: UPF0102 protein Veis_0630 (Veis_0630) from Verminephrobacter eiseniae (strain EF01-2)

KEGG orthology group: K07460, putative endonuclease (inferred from 92% identity to vap:Vapar_4818)

Predicted SEED Role

"Predicted endonuclease distantly related to archaeal Holliday junction resolvase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (122 amino acids)

>GFF3736 UPF0102 protein YraN (Variovorax sp. SCN45)
MKTDTTTKHRGDAAEDAALDHLQDAGLVLVARNYRTPGRGGGEIDLIMRDPRDQTLVFVE
VRQRSTGAHGGAGGSITGLKQRRIVFAARHYLNQLRTLPPCRFDVVLVEEKITWLQAAFD
AA