Protein Info for GFF3729 in Xanthobacter sp. DMC5

Annotation: Ferric uptake regulation protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 143 PF01475: FUR" amino acids 15 to 133 (119 residues), 129.5 bits, see alignment E=3.8e-42

Best Hits

Swiss-Prot: 71% identical to FUR_RHILV: Ferric uptake regulation protein (fur) from Rhizobium leguminosarum bv. viciae

KEGG orthology group: K03711, Fur family transcriptional regulator, ferric uptake regulator (inferred from 94% identity to xau:Xaut_1820)

Predicted SEED Role

"Ferric uptake regulation protein FUR" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases or Iron acquisition in Vibrio or Oxidative stress or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (143 amino acids)

>GFF3729 Ferric uptake regulation protein (Xanthobacter sp. DMC5)
LSGKISLIEEACLAKGMRMTEQRRVIARVLSGAQDHPDVEELHRRAVAIDDNISISTVYR
TVKMLEDAGIIERHDFGDGRARYEQMPDEHHDHLIDLRSGQVIEFRSEEIEALQEQIARQ
LGFKLRGHRLELYAVPLDEDEKQ