Protein Info for PS417_19030 in Pseudomonas simiae WCS417

Annotation: sodium:dicarboxylate symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 7 to 27 (21 residues), see Phobius details amino acids 47 to 70 (24 residues), see Phobius details amino acids 84 to 106 (23 residues), see Phobius details amino acids 151 to 172 (22 residues), see Phobius details amino acids 195 to 219 (25 residues), see Phobius details amino acids 230 to 256 (27 residues), see Phobius details amino acids 266 to 283 (18 residues), see Phobius details amino acids 289 to 330 (42 residues), see Phobius details amino acids 336 to 381 (46 residues), see Phobius details PF00375: SDF" amino acids 8 to 406 (399 residues), 374.7 bits, see alignment E=2.8e-116

Best Hits

Swiss-Prot: 55% identical to GLTP_ECOLI: Proton/glutamate-aspartate symporter (gltP) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to pfs:PFLU4294)

MetaCyc: 55% identical to glutamate/aspartate : H+ symporter GltP (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-122A; TRANS-RXN-162

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UCJ7 at UniProt or InterPro

Protein Sequence (425 amino acids)

>PS417_19030 sodium:dicarboxylate symporter (Pseudomonas simiae WCS417)
MHTPRIALVWQIMIGLLAGIAIGALLHQLPESRPWLVDNLLQPAGDIFIKLMKMIVVPIV
FACMVVGIAGHGDGKSLGRIGARSLGYFFCITTLAIIVGLVLGNLLKPGAGTELSSLHAA
SITLPTSSGAGHSLGQIIVGIIPDNVISAMAQGSLLSVLFFAVMFGLGVARLPAERKDPV
IALLRGVSDAMFKVTSMIMAYSPIGVFGMIAVTVANFGFGSLLPLAKLIMVSYVSIAFFV
LVVLNLVARLCGINLFALMRHIKDELILAFSTASSASVMPQLMKKLETYGVSPSLVSFVV
PVGYSFNLDGASLFLGIGTLFVAQLYGIDLSLGDQALLVVTMVLTSKGAAGVPGFMFVIL
SATLASAGLPLEGIAFIAGVYRLMEMPTTALNVLGNALAPLVIAKWEGRDAKATHEPSAK
NVPSR