Protein Info for PS417_19000 in Pseudomonas simiae WCS417

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 transmembrane" amino acids 16 to 39 (24 residues), see Phobius details amino acids 54 to 75 (22 residues), see Phobius details amino acids 84 to 103 (20 residues), see Phobius details amino acids 109 to 130 (22 residues), see Phobius details amino acids 142 to 164 (23 residues), see Phobius details amino acids 172 to 192 (21 residues), see Phobius details amino acids 215 to 236 (22 residues), see Phobius details amino acids 250 to 268 (19 residues), see Phobius details amino acids 278 to 296 (19 residues), see Phobius details amino acids 302 to 325 (24 residues), see Phobius details amino acids 337 to 359 (23 residues), see Phobius details amino acids 365 to 385 (21 residues), see Phobius details PF07690: MFS_1" amino acids 22 to 349 (328 residues), 129.8 bits, see alignment E=1.2e-41 PF12832: MFS_1_like" amino acids 46 to 168 (123 residues), 25.3 bits, see alignment E=7.7e-10

Best Hits

KEGG orthology group: None (inferred from 92% identity to pfs:PFLU4287)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UI94 at UniProt or InterPro

Protein Sequence (405 amino acids)

>PS417_19000 MFS transporter (Pseudomonas simiae WCS417)
MTPSLTLSASSDRLPIGALLALAMTGFICIVTETLPAGLLPLISEGLAISPSMAGQMVTA
YALGSVLAVIPMTIATRGWRRRNVLLLTIVGFLLFNSITAWSSHYGVTLVARFFAGVAAG
LAWSLLAGYARRMVAPHQQGRALALAMVGTPIALSLGVPLGTWLGGLVGWRTTFGLMSAV
SLVLIVWVLVKVPDYAPQPTHQRLSLGKVLTTPGVRPVLAVVISWMLAHNILYTYIAPFV
APAGLADRVDLVLLVFGVAALAGIWLTAKWVEPLLRRTVLVSLVAFAAMSAVFGLLGNVP
VVIYFGVAVWGLSFGGAATLLQTALADAAGDGADVALSLNVVAWNSAIAGSGVVGGVLLD
TWGVASFPWAMLVLIGVSLAIAWGASAHGFKPGARDAGKPTAVGH