Protein Info for GFF3705 in Xanthobacter sp. DMC5
Annotation: hypothetical protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.
Best Hits
KEGG orthology group: K00201, formylmethanofuran dehydrogenase subunit B [EC: 1.2.99.5] (inferred from 72% identity to xau:Xaut_1796)Predicted SEED Role
"Formylmethanofuran dehydrogenase subunit B (EC 1.2.99.5)" in subsystem Methanogenesis (EC 1.2.99.5)
MetaCyc Pathways
- methyl-coenzyme M oxidation to CO2 II (4/6 steps found)
- methanogenesis from H2 and CO2 (3/6 steps found)
- methyl-coenzyme M oxidation to CO2 I (3/6 steps found)
- reductive acetyl coenzyme A pathway II (autotrophic methanogens) (3/6 steps found)
- methoxylated aromatic compound degradation II (4/9 steps found)
- gluconeogenesis II (Methanobacterium thermoautotrophicum) (10/18 steps found)
- superpathway of methanogenesis (5/21 steps found)
- Methanobacterium thermoautotrophicum biosynthetic metabolism (25/56 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.2.99.5
Use Curated BLAST to search for 1.2.99.5
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (437 amino acids)
>GFF3705 hypothetical protein (Xanthobacter sp. DMC5) MSSGETTEAGAPRIVRDVVCGFCGLGCDDIEVAVTGRVVTPRKACADAARLLARGDAPPP SPRVNGAPASLAEAASAAAAHLKAARSSVFSGLGADLEGHRRLYDIAMVAGASIDHSASG GLFANLDRLARRGWIAATLAEVRNRCDLLVVFGDDPAASFGRLFERIMPVRKGEGGDAAP LFAPSGRRVVMIGAPFSDASRKVLAGHELSEILLPPEQVATAAAMLASALAGRDIGAMDV LPGTAGASLAEIADLLRAARYSVFTWNAATLPQADAAAVAGSASEAVDLLSPTTRAAVLP LGGRDNVTGAHQLALWRFGYPLRTAIGAGTARHAPDLYATAAALKDGDLLLHASAFRPDP PPEFSAGPVIALAHPDTSFAREPDVFIPVGTPGVDHPGHVFRMDSVVCLPLQGLRPAELP SLAEAASAILANFGRGA