Protein Info for GFF3684 in Xanthobacter sp. DMC5

Annotation: Lactate utilization protein B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 PF02589: LUD_dom" amino acids 70 to 298 (229 residues), 164.3 bits, see alignment E=9.5e-52 PF13183: Fer4_8" amino acids 312 to 380 (69 residues), 47.4 bits, see alignment E=8.1e-16 PF13534: Fer4_17" amino acids 315 to 380 (66 residues), 24.6 bits, see alignment E=1e-08 PF11870: LutB_C" amino acids 400 to 472 (73 residues), 27.1 bits, see alignment E=1.5e-09

Best Hits

Swiss-Prot: 41% identical to LUTB_ANOFW: Lactate utilization protein B (lutB) from Anoxybacillus flavithermus (strain DSM 21510 / WK1)

KEGG orthology group: None (inferred from 90% identity to xau:Xaut_1768)

Predicted SEED Role

"Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF" in subsystem L-rhamnose utilization or Lactate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (485 amino acids)

>GFF3684 Lactate utilization protein B (Xanthobacter sp. DMC5)
MSVEITTPRFKDNAKKALADLPLQGALSKVGPGFIGKRAAAAEKLPEFDALRDSARDIKN
HTLAHLDLYLERFEATAKAAGGHVHFAVDAADARAIVTDICKRLGARTVTKGKSMISEEI
GLNDHLAAAGIEPVETDLGEYLIQIRGEAPSHIIAPAIHLNKDQVEADFRRVHAHLPPER
DLSEPTSLLAEARGELRQKFLAADVGITGANFLVAETGTSIIVTNEGNGDLTQTLPKAHI
VLASLEKLVPTLEDVSQILRVLARSATGQDMSVYTTFSTGPRRPDDPDGPGEYHVVILDN
GRSAMLGGQLREVLRCIRCGACMNHCPVYHAVGGHAYGWVYPGPIGSVLTPALIGVEKGR
NLPNASTFCGRCEEVCPMRIPLPKLMRHWREKEFERHLTPATQRFGLGVWAFFARRGWLY
RPATRLAMGALSLLGRAKGRFASLPLAGGWTQHRDFPAPQGGTFQAQWRARQAERRAAPR
QEASR