Protein Info for GFF3658 in Sphingobium sp. HT1-2

Annotation: Tetrapartite efflux system, inner membrane component FusBC-like

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 683 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 36 to 53 (18 residues), see Phobius details amino acids 60 to 78 (19 residues), see Phobius details amino acids 84 to 102 (19 residues), see Phobius details amino acids 109 to 128 (20 residues), see Phobius details amino acids 140 to 159 (20 residues), see Phobius details amino acids 362 to 382 (21 residues), see Phobius details amino acids 388 to 404 (17 residues), see Phobius details amino acids 416 to 435 (20 residues), see Phobius details amino acids 441 to 459 (19 residues), see Phobius details amino acids 465 to 485 (21 residues), see Phobius details amino acids 492 to 510 (19 residues), see Phobius details PF04632: FUSC" amino acids 10 to 667 (658 residues), 583.9 bits, see alignment E=7.9e-179 PF06081: ArAE_1" amino acids 13 to 153 (141 residues), 27.7 bits, see alignment E=4e-10 PF13515: FUSC_2" amino acids 22 to 153 (132 residues), 51.3 bits, see alignment E=2e-17

Best Hits

KEGG orthology group: None (inferred from 44% identity to npp:PP1Y_AT26460)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (683 amino acids)

>GFF3658 Tetrapartite efflux system, inner membrane component FusBC-like (Sphingobium sp. HT1-2)
MADRYGGHDALFTLKAFLAAMLAYYIALRIGLDRPYWAIITAYIVAQPLAGAVSSKAMFR
LLGTVIGAGVAILLVPLLGNAPELLSLALALWLGLCTFVALLDRTPRAYTFLLAGYTAGI
VAFPAVEAQATIFTAASLRAQEIGIGIASATLVHSLVFPRTVSARLQARIDAIMIDAERW
SRDSLRVDHGDAVVTRDRRQLATDIHELNQLATHLPFESSALRLKAGVLRALETQLCLLL
PLASAVEDRCRQLQRANALPPAVHALLDDVVAWLGAPDGEGASPEALRTRARACEPDCRL
PFAWHAALQLSMLDRLAELVAVHAICRELQAAMGADRIPLSPPAREAIRNARRRVLHRDY
GLALRGALATSLTVLIGCLLWILSAWPAGAGAVVIASIICALFSNMDDPAPAAWKVWQGT
CCAVLVAAPYAFAILPRVSDFPVLVAVLAPAFLLVGAMMVRRRLAAMAIGMILSLPGLMG
LDGYYTGQFDSFANAAIAQMLGALLAVWALKMVRTVGAEQSALRLLRAGWRDLALRTDPR
QQPDTVKWINTMLDRIGLLTPRLAELGSDTTAPLLDILRDTRVGMSLDDLHRFRVRAHAR
DDRLLDVVLGRVRQHFDRLGARGQGDPDPALVRAIDTALATIGRNGAVDDRRLALLALTS
LRRNIAPDVPLSLRRDRENSAAA