Protein Info for GFF3651 in Sphingobium sp. HT1-2

Annotation: Uncharacterized UPF0721 integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 transmembrane" amino acids 12 to 47 (36 residues), see Phobius details amino acids 55 to 76 (22 residues), see Phobius details amino acids 92 to 110 (19 residues), see Phobius details amino acids 117 to 136 (20 residues), see Phobius details amino acids 148 to 175 (28 residues), see Phobius details amino acids 186 to 210 (25 residues), see Phobius details amino acids 222 to 245 (24 residues), see Phobius details amino acids 257 to 274 (18 residues), see Phobius details PF01925: TauE" amino acids 16 to 269 (254 residues), 139.3 bits, see alignment E=8.8e-45

Best Hits

KEGG orthology group: None (inferred from 81% identity to sch:Sphch_2605)

Predicted SEED Role

"Protein of unknown function DUF81" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (276 amino acids)

>GFF3651 Uncharacterized UPF0721 integral membrane protein (Sphingobium sp. HT1-2)
MSGDIMTWLVPLVAMLAAGLLAGFAAGIFGIGGGFVVVPALLVVLPLLGGTKDGIAHVAI
GTSAATIILTSIRSLLAHSKRGAVEFDVLKTWAPWIILGCGAGVVLAGHVDGRTLKMIFG
AGVILMSLNFLIPVLNGKVISDQMPSGLARIGIAGGLGTFSSLLGIGGGTIAIMTMTLCG
RTIHRAIATASGIGTLIAIPTTIGFAIIGFREGGLPWGSLGYINIPATIAIASMSMLTAP
LGVAAAHSLPAGPLKKIFGVYLLIIGALMLRAGLKI