Protein Info for GFF3647 in Variovorax sp. SCN45

Annotation: Cytochrome b

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 transmembrane" amino acids 28 to 48 (21 residues), see Phobius details amino acids 55 to 72 (18 residues), see Phobius details amino acids 78 to 95 (18 residues), see Phobius details amino acids 107 to 128 (22 residues), see Phobius details amino acids 162 to 181 (20 residues), see Phobius details amino acids 216 to 233 (18 residues), see Phobius details PF01292: Ni_hydr_CYTB" amino acids 21 to 193 (173 residues), 85.4 bits, see alignment E=2.2e-28

Best Hits

KEGG orthology group: None (inferred from 82% identity to vpe:Varpa_5580)

Predicted SEED Role

"Ni,Fe-hydrogenase I cytochrome b subunit" in subsystem Hydrogenases or Membrane-bound Ni, Fe-hydrogenase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (237 amino acids)

>GFF3647 Cytochrome b (Variovorax sp. SCN45)
MTDSSVAAPRAASGNGTPTRVWDLPTRLFHWALAIAVIGLIGTGLNGIMEWHFRLGYSVF
ALLLFRLVWGFVGGRWSRFGAFIYGPGSVLAYLRGKAHPDHLIGHNPLGALSVFAVLAIL
ALQVATGLTADDEISASGPLTRFVSSEVVSLATGWHKAQGKWIVIALVSLHVLAVLFYAL
VKRHRLVRPMVTGDKLISAGTEGSVASSRDDAASRMFALVVFALCAGAAYWISSLRI