Protein Info for GFF3645 in Xanthobacter sp. DMC5

Annotation: Conjugal transfer protein TraG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 659 transmembrane" amino acids 6 to 31 (26 residues), see Phobius details amino acids 43 to 63 (21 residues), see Phobius details amino acids 75 to 96 (22 residues), see Phobius details PF02534: T4SS-DNA_transf" amino acids 112 to 556 (445 residues), 339.6 bits, see alignment E=4.8e-105 PF10412: TrwB_AAD_bind" amino acids 172 to 535 (364 residues), 87 bits, see alignment E=1.9e-28 PF12696: TraG-D_C" amino acids 401 to 522 (122 residues), 96.3 bits, see alignment E=2e-31

Best Hits

KEGG orthology group: None (inferred from 94% identity to xau:Xaut_0589)

Predicted SEED Role

"Type IV secretion system protein VirD4" in subsystem Type 4 secretion and conjugative transfer or pVir Plasmid of Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (659 amino acids)

>GFF3645 Conjugal transfer protein TraG (Xanthobacter sp. DMC5)
MSATKILWGQILLVFAIVLATTWSATQFVAWRFGFQDQLGPPWFLLGPWPVYPPPAFFWW
WYFYDAYAPAIFTEGGIIAASGGFLSIAAAIGLSVWRAREARRVETYGSARWAEPEEIRA
AGLLGPDGVLLGRHGGDYLRHDGPEHVLCFAPTRSGKGVGLVVPSLLTWPGSAIVHDIKG
ENWQLTAGFRARHGRVLLFDPTNVQSSAYNPLLEVRRGEWEVRDVQNIADILVDPEGSLE
KRNHWEKTSHALLVGAILHVLYAERDKTLAGVAAFLSDPRRPIETTLAAMMTTSHLGEAG
AHPVIASAARELLNKSENERSGVLSTAMSFLGLYRDPVVAEVTRRCDWRITDLVAGGRAT
SLYLVVPPSDINRTKPLIRLILNQVGRRLTEDLQAKAGRHRLLLMLDEFPALGRLDFFES
ALAFMAGYGLKSFLIAQSLNQIEKAYGPNNSILDNCHVRVSFATNDERTAKRVSDALGTA
TEMKAMKNYAGHRLSPWLGHLMVSRSETARPLLTPGEVMQLPPADEIVMIAGTPPIRARK
ARYYEDERFRERVLHPPELLTPRDRQPDDWTVLPLPAPSQLSLMVEGSDDEDTTGSEQRR
QPELARVESVDVPQQSVNEFEIDLADETDDDVARTSRMTRVMQGVARQVSLDPNDGMEL