Protein Info for GFF3636 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: 'Pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5)' transl_table=11

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00558: pyridoxamine 5'-phosphate oxidase
  • amino acids 3 to 218 (216 residues), 333.7 bits, E=2.3e-104
• PF01243: Putative_PNPOx
  • amino acids 41 to 122 (82 residues), 89.5 bits, E=1.3e-29
• PF10590: PNP_phzG_C
  • amino acids 178 to 218 (41 residues), 71.9 bits, 3.3e-24

Best Hits

Swiss-Prot: 100% identical to PDXH_SALNS: Pyridoxine/pyridoxamine 5'-phosphate oxidase (pdxH) from Salmonella newport (strain SL254)

KEGG orthology group: K00275, pyridoxamine 5'-phosphate oxidase [EC: 1.4.3.5] (inferred from 100% identity to sty:STY1674)

MetaCyc: 91% identical to pyridoxine/pyridoxamine 5'-phosphate oxidase (Escherichia coli K-12 substr. MG1655)
Pyridoxal 5'-phosphate synthase. [EC: 1.4.3.5]; 1.4.3.5 [EC: 1.4.3.5]

Predicted SEED Role

"Pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5)" in subsystem Pyridoxin (Vitamin B6) Biosynthesis (EC 1.4.3.5)

MetaCyc Pathways

• superpathway of pyridoxal 5'-phosphate biosynthesis and salvage (11/12 steps found)
• pyridoxal 5'-phosphate biosynthesis I (7/7 steps found)
• pyridoxal 5'-phosphate salvage I (5/6 steps found)
• pyridoxal 5'-phosphate salvage II (plants) (6/9 steps found)
• 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis II (4/8 steps found)

KEGG Metabolic Maps

• Vitamin B6 metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.4.3.5

Use Curated BLAST to search for 1.4.3.5

Protein Sequence (218 amino acids)

>GFF3636 'Pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5)' transl_table=11 (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MSDNDQLQQIAHLRREYTKGGLRRRDLPAEPLTLFERWLGQACDARLADPTAMVVATVDD
KGQPYQRIVLLKHYDEKGLVFYTNLGSRKAHQIEHNPRISLLFPWHMLERQVMVTGKAER
LSTLEVVRYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGG
FRVSIEQMEFWQGGEHRLHDRFLYQRDDGAWKIDRLAP