Protein Info for GFF3631 in Sphingobium sp. HT1-2

Annotation: ABC transporter, ATP-binding protein (cluster 10, nitrate/sulfonate/bicarbonate)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 PF00005: ABC_tran" amino acids 39 to 165 (127 residues), 94 bits, see alignment E=1.2e-30

Best Hits

Swiss-Prot: 59% identical to SSUB1_PSEF5: Aliphatic sulfonates import ATP-binding protein SsuB 1 (ssuB1) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)

KEGG orthology group: K02049, sulfonate/nitrate/taurine transport system ATP-binding protein (inferred from 85% identity to sjp:SJA_C2-04320)

Predicted SEED Role

"Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB" in subsystem Alkanesulfonate assimilation or Alkanesulfonates Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (263 amino acids)

>GFF3631 ABC transporter, ATP-binding protein (cluster 10, nitrate/sulfonate/bicarbonate) (Sphingobium sp. HT1-2)
MDARLGFSTIDSAAHQPHPEPVVRLQHFTRSFGANRIIDGLDLEIAPGEFIALLGRSGSG
KTTLLRTLAGLDDAGAQDVEVPDSRAVVFQDARLLPWKPVWKNVALGLKGDAIRDRAQAA
LKEVGLGHRLDAWPLTLSGGEAQRAALARALVREPQLLLLDEPFAALDALTRYRMHDLVL
SLWRTHKPAVLIVTHDVEEAIALADRVLVLDKGRIVAEERIHAARGERAGLAGRLREQLL
SHLGGDHHGEGVLPFARQAEAAE