Protein Info for GFF3626 in Variovorax sp. SCN45

Annotation: Hydrolase, alpha/beta fold family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 210 transmembrane" amino acids 102 to 122 (21 residues), see Phobius details PF02129: Peptidase_S15" amino acids 24 to 117 (94 residues), 27.7 bits, see alignment E=4.6e-10 PF00561: Abhydrolase_1" amino acids 49 to 135 (87 residues), 27.3 bits, see alignment E=5.5e-10

Best Hits

KEGG orthology group: K07018, (no description) (inferred from 88% identity to vpe:Varpa_5601)

Predicted SEED Role

"Alpha/beta hydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (210 amino acids)

>GFF3626 Hydrolase, alpha/beta fold family (Variovorax sp. SCN45)
MNSQTEKITLQGAAGRIEVQRDQPAEAPRGVAVIAHPHPLFSGTMDNKVVQTLARAFVAS
GWTSVRFNFRGVGASEGVHDEGRGELEDMLNVVGQLAPEGPLAIAGFSFGAFVASGAVSR
LWGERDVRQIVLVGTAAARNVVAPLPVEARERALVIHGEADDTVALSAVMDWARPQSLPV
TVIPGGGHFFHGQLPLLKSLVARHLRAGAA