Protein Info for GFF3617 in Sphingobium sp. HT1-2

Annotation: FIG138928: iron-regulated membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 522 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 139 to 161 (23 residues), see Phobius details amino acids 188 to 214 (27 residues), see Phobius details amino acids 338 to 360 (23 residues), see Phobius details amino acids 381 to 400 (20 residues), see Phobius details amino acids 412 to 431 (20 residues), see Phobius details amino acids 438 to 459 (22 residues), see Phobius details amino acids 474 to 494 (21 residues), see Phobius details PF03929: PepSY_TM" amino acids 11 to 361 (351 residues), 210.4 bits, see alignment E=2.7e-66

Best Hits

Predicted SEED Role

"FIG138928: iron-regulated membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (522 amino acids)

>GFF3617 FIG138928: iron-regulated membrane protein (Sphingobium sp. HT1-2)
MKASLRQTMSTLHTWTGLLPGWLLFVIFLFGTVAFFQQEISQWMRPELTPAPVSDKAIDA
ADTILRKEGAGADDWTLSLPGSRGGDGFSISWTPAGGDRSSQQERTLDATSGALTSVRDT
RGGFFLYRMHFDLHYMPVMWARLLVSLAALAMLVAILSGVVTHKKIFTDFFLLRFGKGQR
SWLDAHNVTAVLALPFYLMITYTGLVTLLFTLMPWAISANFPSTDAYYEAAFPSGPKSEP
SETKAVLRPIPELLQRARTLRPGFEPSYVSISHPGNAAAIVRIWPRTETLGGHQPMLYLN
GATGEPLAGPREGGAATATKGVMIDLHAGRYANPALRWLYFLSGVGGTIMVGSGLVLWTV
KRRAKLPDPARPHFGFRLVERLNIGVIAGASAGIAVYFLANRLLDPTMVGRADWEVNALF
IAWGAIFIWSLGRPARQAWVETLAACALLYAAIPLVNAATTPRGLPASVMAGDAIFILFD
LMMTLTATGFAFAARKVATHQSKAKARSRTRQPKQDFQEVPA