Protein Info for PS417_01835 in Pseudomonas simiae WCS417

Annotation: twin-arginine protein translocation system subunit TatC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 transmembrane" amino acids 25 to 47 (23 residues), see Phobius details amino acids 80 to 101 (22 residues), see Phobius details amino acids 113 to 139 (27 residues), see Phobius details amino acids 162 to 188 (27 residues), see Phobius details amino acids 199 to 217 (19 residues), see Phobius details amino acids 223 to 241 (19 residues), see Phobius details TIGR00945: twin arginine-targeting protein translocase TatC" amino acids 14 to 231 (218 residues), 249.9 bits, see alignment E=1.3e-78 PF00902: TatC" amino acids 16 to 226 (211 residues), 240.3 bits, see alignment E=9.7e-76

Best Hits

Swiss-Prot: 72% identical to TATC_AZOCH: Sec-independent protein translocase protein TatC (tatC) from Azotobacter chroococcum mcd 1

KEGG orthology group: K03118, sec-independent protein translocase protein TatC (inferred from 97% identity to pfs:PFLU0382)

MetaCyc: 62% identical to twin arginine protein translocation system - TatC protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-181

Predicted SEED Role

"Twin-arginine translocation protein TatC" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UBL4 at UniProt or InterPro

Protein Sequence (262 amino acids)

>PS417_01835 twin-arginine protein translocation system subunit TatC (Pseudomonas simiae WCS417)
MSADKPENDQHMPLVSHLTELRTRLLRCVAAIFIIFAGLFAFTQQIYTFVSTPLRQYLPA
GATMIATDVSSPFLTPLKLTMMVSLFLAIPVILHQIWGFIAPGLYKHEKRIAVPLLVSSI
LLFYTGMAFAYFLVFPLIFKFFAAATPAGVEMMTDITSYLDFVMTLFFAFGVAFEIPVAV
VLLVWIGVVNVAYLKKIRPYVIIGCFVVGMILTPPDIFSQTLLAVPMWMLFEIGILFSGL
ISKRGEHPDDQPDDDQPPATQP