Protein Info for GFF36 in Variovorax sp. SCN45

Annotation: Similar to Agmatine deiminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF04371: PAD_porph
  • amino acids 45 to 373 (329 residues), 361.6 bits, E=2e-112

Best Hits

KEGG orthology group: K10536, agmatine deiminase [EC: 3.5.3.12] (inferred from 84% identity to del:DelCs14_3637)

Predicted SEED Role

"Agmatine deiminase (EC 3.5.3.12)" in subsystem Arginine and Ornithine Degradation or Polyamine Metabolism (EC 3.5.3.12)

MetaCyc Pathways

• superpathway of polyamine biosynthesis II (6/8 steps found)
• L-arginine degradation IV (arginine decarboxylase/agmatine deiminase pathway) (2/3 steps found)
• putrescine biosynthesis II (2/3 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Urea cycle and metabolism of amino groups

Isozymes

Compare fitness of predicted isozymes for: 3.5.3.12

Use Curated BLAST to search for 3.5.3.12

Protein Sequence (374 amino acids)

>GFF36 Similar to Agmatine deiminase (Variovorax sp. SCN45)
MTAKVPFFEETDMRPSLARRRLLAGMGLAPLALAAPSMAAAESWHMPDEGDPHRATWMSF
GPSEEVWGRRLLKPAREHLAGIARTIAAFEPVRMLVNEEDHDLAARLCGNKVELEVQPVD
DLWMRDTGPVFVRNAGGQWAGVDFNFNGWGRKQAHERDAEVAEYVTDAAEVQRLRTRLVL
EGGGIEVDGAGTAIITESCVLNANRNPGLNKEACEAELKRLLGLRKIIWLPGIAGRDITD
GHTDFYARFASPGVVVAGLDEDPGSYDRAVTRRHLEILKQATDAHGQKLRVEVLKGPESV
RKKLETPEFAAGYINFYVCNGAVIAPQFGDARADANARSLLRELFPKREVVQLDIDGIAA
GGGGIHCTTQQQPR