Protein Info for PS417_18385 in Pseudomonas simiae WCS417

Annotation: ribokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00294: PfkB
  • amino acids 3 to 295 (293 residues), 244.3 bits, E=2e-76
• TIGR02152: ribokinase
  • amino acids 5 to 300 (296 residues), 373.1 bits, E=5.2e-116
• PF08543: Phos_pyr_kin
  • amino acids 180 to 277 (98 residues), 40.3 bits, E=2.6e-14

Best Hits

KEGG orthology group: K00852, ribokinase [EC: 2.7.1.15] (inferred from 96% identity to pfs:PFLU4156)

MetaCyc: 40% identical to deoxyribokinase monomer (Salmonella enterica enterica serovar Typhi)
RXN-14223 [EC: 2.7.1.229]

Predicted SEED Role

"Ribokinase (EC 2.7.1.15)" in subsystem D-ribose utilization or Deoxyribose and Deoxynucleoside Catabolism (EC 2.7.1.15)

MetaCyc Pathways

• 2-deoxy-D-ribose degradation I (2/3 steps found)
• ribose phosphorylation (1/2 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.15 or 2.7.1.229

Sequence Analysis Tools

See A0A1N7U3V5 at UniProt or InterPro

Protein Sequence (305 amino acids)

>PS417_18385 ribokinase (Pseudomonas simiae WCS417)
MPAKVVVVGSLNMDLVTRASRLPRAGETLIGQTFSTVPGGKGANQAVASARLGADVSMIG
CVGSDAYGSQLREALLVEGIDCQAVSTVDGSSGVALIVVDDSSQNAIVIVAGSNGELTPA
SLQAFDAVLQAADVIVCQLEVPMNTVGYALKRGRELGKTVILNPAPASGPLPAEWYASID
YLIPNESEASALSGVTVDSIDAAKVAATQLIQAGAGKVIVTLGAQGALFTDGQRFEHLQA
PKVKAVDTTAAGDTFVGGFAAALANGKSEAEAIRFGQVAAALSVTRAGAQPSIPTLHDVQ
GFVPS