Protein Info for PS417_18145 in Pseudomonas simiae WCS417

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 transmembrane" amino acids 7 to 30 (24 residues), see Phobius details amino acids 127 to 149 (23 residues), see Phobius details PF00512: HisKA" amino acids 204 to 261 (58 residues), 49.1 bits, see alignment E=4.9e-17 PF02518: HATPase_c" amino acids 312 to 416 (105 residues), 78.6 bits, see alignment E=4.9e-26

Best Hits

KEGG orthology group: None (inferred from 98% identity to pfs:PFLU4102)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TZ61 at UniProt or InterPro

Protein Sequence (427 amino acids)

>PS417_18145 histidine kinase (Pseudomonas simiae WCS417)
MTKPSLLFWKLFLAFWLATTLTFLVGVGVLELSRFRPGDPHVGAILASEQKLLEQFGVQA
AGQFLAVWERPPDEVIGIYDRTGQLLAGSAVAEPAFERAVTSKEGLALSLRSSHAPGDDG
GRPWQQVPLIIGTLMSALFSGYMAYYLAWPLAHLRRAMSDVAQGRFETRVKPSMGKRRDE
IVDLAEDCDRMANQLKVLVQAQHHLLHDISHELRSPLTRMQAAIGLLRQDAARLEMLERI
ERECERMDTLIEALLTLARLQGRPESIEREPVDIVELLAMIVDDAQFEAGIKDCRVHLQA
CPPFIACVSGELLYRCFENVIRNAVRYTRPGTTVQVSAQVNREANRLSVRISDLGPGVAP
DRLSTIFQPFERGVGDATVGFGLGLAIAARAVQMHGGHIEARNESGGGLTVEINLHSARS
LHDITLA