Protein Info for PS417_18090 in Pseudomonas simiae WCS417

Annotation: iron ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 PF00005: ABC_tran" amino acids 20 to 168 (149 residues), 114.3 bits, see alignment E=1e-36 PF13304: AAA_21" amino acids 31 to 54 (24 residues), 28.8 bits, see alignment (E = 2e-10)

Best Hits

Swiss-Prot: 56% identical to FECE_ECOLI: Fe(3+) dicitrate transport ATP-binding protein FecE (fecE) from Escherichia coli (strain K12)

KEGG orthology group: K02013, iron complex transport system ATP-binding protein [EC: 3.6.3.34] (inferred from 90% identity to pfs:PFLU4088)

MetaCyc: 56% identical to ferric citrate ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-9-RXN [EC: 7.2.2.18]

Predicted SEED Role

"Iron(III) dicitrate transport ATP-binding protein FecE (TC 3.A.1.14.1)" (TC 3.A.1.14.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.34

Use Curated BLAST to search for 3.6.3.34 or 7.2.2.18

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UNJ8 at UniProt or InterPro

Protein Sequence (263 amino acids)

>PS417_18090 iron ABC transporter (Pseudomonas simiae WCS417)
MSILQARELDIGYGTTRIVQGLSFVPPTGKVTALIGPNGCGKSTLLKAFARILKPTQGEL
TLDGHAYTSLSARQLARQIAFLPQVLPVPEGVSVRQLVAYGRSPHNSLWGRLSGNDQAHV
TQAMQRLELDTLADRALADLSGGQRQRAWLAMVLAQNAPVVLLDEPTTYLDISHQVELLD
LMGELAGEGKTVITVLHDINQACRYAHHLAVMHGGKLVADGAPGQVITAELMRQVFEVQV
QVMSEPVAGTPMCLIKKSTRPHT