Protein Info for PS417_18050 in Pseudomonas simiae WCS417

Annotation: general secretion pathway protein GspL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 transmembrane" amino acids 174 to 192 (19 residues), see Phobius details PF05137: PilN" amino acids 245 to 316 (72 residues), 38.5 bits, see alignment E=9.6e-14

Best Hits

KEGG orthology group: K02461, general secretion pathway protein L (inferred from 74% identity to pfs:PFLU4073)

Predicted SEED Role

"General secretion pathway protein L"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UEB1 at UniProt or InterPro

Protein Sequence (330 amino acids)

>PS417_18050 general secretion pathway protein GspL (Pseudomonas simiae WCS417)
MNRLEPIARHWRGSLLQQGWRVWLAELRACVPSWLARPEPPEQIHHWPLAVPVVSSSTRQ
VLMLGADAVLLQRVQLPLAAGRNLEAVVGYELDRYTPFEADQLYCVARQERRTPSHLEVT
LVAILRERLDQMLTDCAALGLHPHRVDAANLGIDLLPAPLRPRQHRPGMGLQRSLPWLCG
ALLIAAMVLWLNDRQRVIDVMHTSVQQQKAQVAEVHALRQQLLNTRGAAQYLTRRKLAQP
PLAALLNDLTTCLPADTWLDQLEVKDGEISISGQSAKASALITRIKGCRSLENAQFEGVI
QPDARTGKDQFALRAHLRQEAADAPTPHTP