Protein Info for GFF349 in Sphingobium sp. HT1-2

Annotation: Capsule polysaccharide export protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 558 PF05159: Capsule_synth" amino acids 249 to 325 (77 residues), 29.8 bits, see alignment E=2.2e-11 amino acids 350 to 506 (157 residues), 101.3 bits, see alignment E=3.7e-33

Best Hits

KEGG orthology group: K07266, capsular polysaccharide export protein (inferred from 68% identity to sjp:SJA_C1-33120)

Predicted SEED Role

"Capsular polysaccharide export system protein KpsC" in subsystem Rhamnose containing glycans

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (558 amino acids)

>GFF349 Capsule polysaccharide export protein (Sphingobium sp. HT1-2)
MADAGVVACRRADRVPFLRSPPFPGIDPAVAAISQDDQGCFSAPISDGLLDALRLARVGG
DFWGHRPKGLLLVAREGVRIDPSICIGLVAGQIGIMPADVSAKRGAAPAIGHWLPSVCDP
WVLLADARTVHAEVDDDLAIVAGLLGIAVFGPDGAAFSAEQLKEAARYRLASARYRDCFS
GEMVDAAHAIAQLADWRRHVDGNRGIAAASGMAFWKREAMRHFLWDGVRTPPFLSPARGL
TRARREAGALAIWPSRVPVTITADAAAVGVTLARVEDGFLRSGGLGAALHPPGSVVIDRC
GIYYNARAASDLEGLLATHEFSPDLVERARQLRARVCDAGVTKYGAEAGQMIDLPPGRRT
VLAVGQVDDDMSVQLGGAGVDGNLDFLARVRRAEPDAWIIYRPHPDVQAGHRKGHLSDAV
VLEHADAIDSGAPLMELVQAVDDVHVLSSLTGFEALMRGCSVTVHGMPFYAGWGLTRDLA
KSSPRRGRQLDVDRLVAAALILYPRYIDPVTCLPCGPELMVDRLASGSTPPMTWLIRLRG
LQGKLRRFMTLSAEFLHG