Protein Info for GFF3480 in Sphingobium sp. HT1-2

Annotation: ATP-dependent RNA helicase Atu1833

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 PF00270: DEAD" amino acids 25 to 193 (169 residues), 167.1 bits, see alignment E=4.6e-53 PF04851: ResIII" amino acids 40 to 187 (148 residues), 32.1 bits, see alignment E=1.6e-11 PF00271: Helicase_C" amino acids 229 to 337 (109 residues), 111.9 bits, see alignment E=3e-36

Best Hits

KEGG orthology group: None (inferred from 88% identity to sch:Sphch_0340)

Predicted SEED Role

"ATP-dependent RNA helicase Atu1833" in subsystem ATP-dependent RNA helicases, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (463 amino acids)

>GFF3480 ATP-dependent RNA helicase Atu1833 (Sphingobium sp. HT1-2)
MTFADLGLSDELLKAVTEAGYDTPTPIQAQAIPPVLMMKDIIGIAQTGTGKTASFVLPMI
DILAHGRARALMPRSLILEPTRELAAQVAENFEKYGKYHKLSMALLIGGVQMGDQIKALE
KGVDVLIATPGRLMDLFQRGKILLNGCNMLVIDEADRMLDMGFIPDIEEICTKLPAQRQT
LLFSATMPPVIKKLADRFLDNPKSIEVARPATASTNITQRLVKVDSRKKREALRAMLEAE
DVQSAVIFCNRKTTVRELNKSLQRHGFKSGEIHGDIDQASRIAELERFRDGSVNILVASD
VAARGLDIKGVSHVFNFDAPWHPDDYVHRIGRTGRAGAKGVAYTFVAAEDAEAIDNIQKL
IGTKIDYVETPVAAAPAPRAKEEPRKADREERDNERSGGREARRKPERKDDRRSDKRDDR
RDDRRDAPAARSAPHSRRQEPDDGPDDGWNGPVPEFLNFGFGG