Protein Info for GFF3479 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00357: methionine-R-sulfoxide reductase
  • amino acids 5 to 134 (130 residues), 213.8 bits, E=3.9e-68
• PF01641: SelR
  • amino acids 9 to 127 (119 residues), 183.2 bits, E=7.5e-59

Best Hits

Swiss-Prot: 100% identical to MSRB_SALSV: Peptide methionine sulfoxide reductase MsrB (msrB) from Salmonella schwarzengrund (strain CVM19633)

KEGG orthology group: K07305, peptide-methionine (R)-S-oxide reductase [EC: 1.8.4.12] (inferred from 99% identity to sea:SeAg_B1884)

MetaCyc: 85% identical to methionine sulfoxide reductase B (Escherichia coli K-12 substr. MG1655)
L-methionine (R)-S-oxide reductase. [EC: 1.8.4.14]; Peptide-methionine (R)-S-oxide reductase. [EC: 1.8.4.14, 1.8.4.12]

Predicted SEED Role

"Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12)" (EC 1.8.4.12)

KEGG Metabolic Maps

• Methionine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.4.12 or 1.8.4.14

Protein Sequence (137 amino acids)

>GFF3479 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKY
DSGCGWPSFYQPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVN
SASLAFSDEKNGDQLKG