Protein Info for GFF3477 in Variovorax sp. SCN45

Annotation: Phosphoprotein phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 522 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details PF00149: Metallophos" amino acids 178 to 422 (245 residues), 46 bits, see alignment E=4.5e-16

Best Hits

KEGG orthology group: None (inferred from 68% identity to rme:Rmet_5304)

Predicted SEED Role

"Phosphoprotein phosphatase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (522 amino acids)

>GFF3477 Phosphoprotein phosphatase (Variovorax sp. SCN45)
MHAMLALPRAFSESRRLRRLAALAGLAAAATLLQACNGGSDNQTVVLGPPPAPAPAPAPA
PAPDAASADANLQAAWVEIGENNAAIARVITSYTAPAAATTADANAVCPQLTVDGKAMRM
TLRIGAGTMALRTTASDPVDSKPSAFPVSTCETTLPASAKQAAVGSRALPLPKAEPQRVL
VLADTGCRMKKADKAFQPCNDSTVWPFAPLAAMGASFNPDLVMHIGDYHYRENECPSDNS
GCKSSPWGYGWDTWQADFFAPAAPLLAKAPWVLVRGNHEECARAGQGWARFLDPRPYADK
RSCNDPANDDSGNYADPYAVALGTGSQVIVFDSAKAGKVALATNDPQFIAYQKQFQAVTA
LANKPGMTTTMFTNHHPILGFAPTPTDPLPGNLALQSVMKSVNATAYYPAGVHVALHGHV
HDFQALNFSTDHPATLVTGNGGDNLDFAITDPLPAGATPAPGVTVDRITHHNTFGFMLME
RKAAPGVGWNFKAYTVVGKLLATCVQTGRALACDKTGLLVTP