Protein Info for GFF3472 in Sphingobium sp. HT1-2

Annotation: ATP synthase F0 sector subunit a (EC 3.6.3.14)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 261 transmembrane" amino acids 33 to 55 (23 residues), see Phobius details amino acids 67 to 84 (18 residues), see Phobius details amino acids 90 to 115 (26 residues), see Phobius details amino acids 126 to 146 (21 residues), see Phobius details amino acids 152 to 176 (25 residues), see Phobius details amino acids 184 to 207 (24 residues), see Phobius details amino acids 219 to 253 (35 residues), see Phobius details TIGR01131: ATP synthase F0, A subunit" amino acids 11 to 257 (247 residues), 202.8 bits, see alignment E=3.6e-64 PF00119: ATP-synt_A" amino acids 39 to 255 (217 residues), 205.8 bits, see alignment E=4e-65

Best Hits

Swiss-Prot: 76% identical to ATP6_ERYLH: ATP synthase subunit a (atpB) from Erythrobacter litoralis (strain HTCC2594)

KEGG orthology group: K02108, F-type H+-transporting ATPase subunit a [EC: 3.6.3.14] (inferred from 94% identity to sjp:SJA_C1-22640)

Predicted SEED Role

"ATP synthase F0 sector subunit a"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (261 amino acids)

>GFF3472 ATP synthase F0 sector subunit a (EC 3.6.3.14) (Sphingobium sp. HT1-2)
VAESGKIDPMHQFAIEPLFGTDHLSIGGFNIAFTNSALYMVAAAVVLWIFVIGGMKRELV
PGRWQMAVEYFTGFIKNLLISNVGEGGKKYIPYVFSLFMFILMANLLGLLPLGLVGVHPF
TFTSHFTATGVLAIMSFSIVLIVGFWKHGLHFFSLFVPHGTPLPMIPVIFPIELISFMVR
PFSLGLRLFVAMTAGHVLLKVLAGFVINSSNAGPGFGLTVGAASFVLMVGISALEVLVAV
IQAYVFALLTSVYINDAENLH