Protein Info for GFF3442 in Sphingobium sp. HT1-2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 714 transmembrane" amino acids 38 to 57 (20 residues), see Phobius details amino acids 454 to 474 (21 residues), see Phobius details PF02706: Wzz" amino acids 31 to 116 (86 residues), 36.3 bits, see alignment E=1.1e-12 TIGR01007: capsular exopolysaccharide family" amino acids 514 to 711 (198 residues), 151.4 bits, see alignment E=1.2e-48 PF01656: CbiA" amino acids 532 to 645 (114 residues), 25.8 bits, see alignment E=1.8e-09 PF13614: AAA_31" amino acids 542 to 661 (120 residues), 47.9 bits, see alignment E=3.2e-16

Best Hits

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.10.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (714 amino acids)

>GFF3442 hypothetical protein (Sphingobium sp. HT1-2)
MVSRIIELEQRQAGEEDRTTRFVESARGTWTVVRRHRVILFVTMALCVLAGVIYILLSTP
DYRATASVEVEDVPAGAAGAGAMQKPVSAADTESMMQTELEVLRSRALAEDVARDLALVG
SPVFFQGMDARRPAQGQGSLTQRQVEHEQVIKLLRDNLQVELPGKSRVLRISFVSADPAL
SARVANSYADSLIRADLKRGFESGVQARRFLLGELDGARKDLERAERDLAVYASRTGAVP
AEAATDEDKKSDGKDAKPDAAPVPEGSTAARLAQLNAFRAQAVADRIAAQKRWESAKAAS
AETLPEVLGNGAMQQLMAERAQARAALVEERQFRKDAHPEMREARARLAALDDQAESMAN
TIRASLRQEYEVAAHGEKQIASEIAALEGDARVERGRDMQMSMMSRSVETYRLLHDSLLQ
RYRDMASQAGFQAGRIQPLDRAAVPTTPFAPHAGQIMLVALFGGMLLGLLLIAARHMFDD
AVTSADTLAERVDLPLLGAVPTTGDQPSAPDIFAPIAASLQLASVAGLPRSILVTSAQEE
EGKSLTVNALARALARLDKKVLVIDADMRRPVQHSLFRVTATRGISEVLTGQGKVEDLIL
DSGVAGVSLLPCGAVPPNPAELLSTPALDALLGAVRDRYDTVLIDAPPILGMSDAQLLAA
KVQVTLLVVEWGRNHHGGLRVAVERLRRAGGSIVGAVLTKAHGRAYDYDYHRGG