Protein Info for GFF3425 in Xanthobacter sp. DMC5

Annotation: putative FMNH2-dependent monooxygenase SfnC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 PF02771: Acyl-CoA_dh_N" amino acids 29 to 121 (93 residues), 29.6 bits, see alignment E=7.8e-11 PF08028: Acyl-CoA_dh_2" amino acids 241 to 378 (138 residues), 38.8 bits, see alignment E=1.1e-13

Best Hits

KEGG orthology group: None (inferred from 83% identity to xau:Xaut_2768)

Predicted SEED Role

"Acyl-CoA dehydrogenase; probable dibenzothiophene desulfurization enzyme"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (413 amino acids)

>GFF3425 putative FMNH2-dependent monooxygenase SfnC (Xanthobacter sp. DMC5)
MSQIEDAWGAGPTDRYEELASRFRPIFRDIRDSAVEREQTHRLPRAEIAALKEAGFTTLR
LPKDEGGFGATLPELFNLLIELSEADSNVTNALRAHFGFTEEVLNSPFKDYRDRWVKRIA
AKQTSGSGFTEGSDNAVGHFNTRIVRDGDRLRLDGQKFYTTGSLFADWINLGAEDEGGNF
ILAQVPTGAPGVSIVDDWDGFGQQLTASGTAKFDNVTLSDDLINPQRKRFRYSVAFYQLV
HLATLAGIGRAAAGDVARLVSVRKRVFSHGNADRAGADPQILQIVGKVRASAYGAGAVVL
KAAEALQRAYDTRERETSEGQDVSVAVADLEVNQGVTVVTSLILDATSHLFDALGASSAR
RGVGLDRHWRNARTLSSHNPRVYRERIVGDFAVNGTWPPGPYRVGDGIAAKAG