Protein Info for GFF3424 in Sphingobium sp. HT1-2

Annotation: Alr3170 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 581 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 150 to 308 (159 residues), 91.5 bits, see alignment E=2.3e-30 PF00990: GGDEF" amino acids 151 to 305 (155 residues), 115.2 bits, see alignment E=2.6e-37 PF00563: EAL" amino acids 326 to 562 (237 residues), 222 bits, see alignment E=7.7e-70

Best Hits

KEGG orthology group: None (inferred from 85% identity to sjp:SJA_C1-14790)

Predicted SEED Role

"Alr3170 protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (581 amino acids)

>GFF3424 Alr3170 protein (Sphingobium sp. HT1-2)
MSVRSWPPEQTSGLPLPGGDDTHLPHMIGASEWLTALSQAAAILSCENNAINIVEANEPF
LKAFREHRERTAATAQASAEWRARVTGFAQSDRDSESFEIRRDGKLGPEYFLCTLGRLRA
TGARAEQFLFTAIDRTSERTMEKNLRRELLSDGLTALPNRTGFGEEIDDRLANGSWPENA
QFGIIAIDLSRFSRVNESLGPMAGDELLITVAKRLKSCLRQGDVLARIGGNDFAIFARLN
NGLSDSLQIVQRIREALSSPIRLSDLQIRVDCAIGCALSTHLEDDPDDVVRKAQAAVKIA
KRTGKVEIYRNGVLKEAQRRFSIESRLRDALAHGGLTLAYQPLIHLQTGEITGFEALARW
DDPELGHVSPVEFVPVAEESGLITPLGRWAAYEAAQALSRWDAKFGQALPVGVNVNLSPI
QMARDDVASMFEEALRYSGIGGHRLTAELTESAIIADPDKARKLLFALKDLQMPIAMDDF
GTGFSNLASLHSLPIDILKIDRSFVSNMLEDHDKAVIVRTILSLAESLNLRVTAEGIETQ
ELADMLQKMGCWQGQGYYFARPMSEADAFDYWRVRWNFETI