Protein Info for GFF3419 in Xanthobacter sp. DMC5

Annotation: Glutathione transport system permease protein GsiC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 111 to 133 (23 residues), see Phobius details amino acids 142 to 166 (25 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 252 to 277 (26 residues), see Phobius details amino acids 297 to 320 (24 residues), see Phobius details PF19300: BPD_transp_1_N" amino acids 13 to 111 (99 residues), 27.5 bits, see alignment E=3e-10 PF00528: BPD_transp_1" amino acids 123 to 328 (206 residues), 150.2 bits, see alignment E=5.7e-48

Best Hits

Swiss-Prot: 43% identical to APPB_BACSU: Oligopeptide transport system permease protein AppB (appB) from Bacillus subtilis (strain 168)

KEGG orthology group: K02033, peptide/nickel transport system permease protein (inferred from 81% identity to azc:AZC_2660)

Predicted SEED Role

"Dipeptide transport system permease protein DppB (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (330 amino acids)

>GFF3419 Glutathione transport system permease protein GsiC (Xanthobacter sp. DMC5)
MTTRRLPRILKAVRRTALQAVPTVIGILILNFFLLRLTPGDAADALAGEAGAATVETLAA
LKSKFGLDLPVLEQLGGYLSNLAHFSLGVSPRYNQPVAELIAARLPNTLSLMGLALVFAL
VIGITLGALMASFAGRPTDRVLSVVALLFYSIPSFWIGLMLIVLFSVNLGWLPTGGAETI
GANLTGWDAVLDRARYQILPALSLALFYVAIYARLTRDDMIEVRTQDHVRTARAKGLSPF
AVTRDHVLRNALIPVTTMAGIHLAGLMGGAVVVETVFSWPGLGRLAYEAVMGRDFHVLLG
ILLLSSLLVVAVNAAIDILQAWLDPRIEVR