Protein Info for PS417_17470 in Pseudomonas simiae WCS417

Annotation: LuxR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 208 PF00072: Response_reg" amino acids 3 to 115 (113 residues), 99.5 bits, see alignment E=2e-32 PF08281: Sigma70_r4_2" amino acids 139 to 186 (48 residues), 26 bits, see alignment 8.5e-10 PF00196: GerE" amino acids 144 to 197 (54 residues), 58.6 bits, see alignment E=5.7e-20

Best Hits

Swiss-Prot: 70% identical to EXAE_PSEPU: Transcriptional activator protein ExaE (exaE) from Pseudomonas putida

KEGG orthology group: None (inferred from 84% identity to pfl:PFL_2212)

MetaCyc: 32% identical to DNA-binding transcriptional dual regulator NarL (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"DNA-binding response regulator, LuxR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UE07 at UniProt or InterPro

Protein Sequence (208 amino acids)

>PS417_17470 LuxR family transcriptional regulator (Pseudomonas simiae WCS417)
MNILLVDDHAVVRQGYASLLRALLPAVEVREAASGEEALSRVQEALPHLVIMDFGLPGIS
GLETTRRLRQRLPHLRVLFFSMHDELPLVRQALDAGASGYLTKTSAPEVLIEAVRRILDG
HAYIEQALATELAYTPSDQRLQGMTPRELEIFLMLARGTPTRAIADQLNISSKTVSNHLT
LLKSKLQVSSHAELVHLGIDMGVVRVVG