Protein Info for PS417_17440 in Pseudomonas simiae WCS417

Annotation: beta-lactamase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details TIGR04558: quinoprotein relay system zinc metallohydrolase 1" amino acids 19 to 303 (285 residues), 430.4 bits, see alignment E=1.3e-133 PF00753: Lactamase_B" amino acids 47 to 231 (185 residues), 90.3 bits, see alignment E=8.3e-30

Best Hits

KEGG orthology group: None (inferred from 80% identity to pfl:PFL_2220)

Predicted SEED Role

"SoxH protein, homolog" in subsystem Sulfur oxidation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U107 at UniProt or InterPro

Protein Sequence (310 amino acids)

>PS417_17440 beta-lactamase (Pseudomonas simiae WCS417)
MRWILLLCLGLSLPALADLDYALKPRLIADDTWLLEGSTDNFAKANGGNIVNTAFIVTEA
GVVVIDTGPSRRYGEAMREAIARVTPKPVTQVLITHHHPDHALGNQAFKDVPIGALAETT
RLLHEQGDGMAENLYRMVGDWMRGTEVVLPTQVLEPGVLSVGRHDLRLLALTGHTGADLA
IFDQSTGVLFAGDLVFYQRALTTPNSPGLAVWLADLGTLQALPWTLIVPGHGPVASDAQP
FTQMRDYLTWLDQLLRDGAAHGSDMAEMIRSPIPERFATISLSRYELIRSVSHLYPRYER
ERMQRVDSAR