Protein Info for PS417_17415 in Pseudomonas simiae WCS417

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 456 PF00512: HisKA" amino acids 98 to 161 (64 residues), 40.3 bits, see alignment E=4e-14 PF02518: HATPase_c" amino acids 207 to 315 (109 residues), 71.1 bits, see alignment E=1.5e-23 PF00072: Response_reg" amino acids 342 to 451 (110 residues), 43.6 bits, see alignment E=4.7e-15

Best Hits

KEGG orthology group: None (inferred from 81% identity to pba:PSEBR_a2668)

Predicted SEED Role

"Sensory box histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TYW9 at UniProt or InterPro

Protein Sequence (456 amino acids)

>PS417_17415 histidine kinase (Pseudomonas simiae WCS417)
MAKRSEDQQQALAGLLGLGNHSARKSHYPELTARLDELEAERNRYIRLNDELEQRVAVRT
DELLEANRNLQQQIAQREQVEQELRDARDAAEAANRSKDKYLAAASHDLLQPLNAARLLI
STLRERNLPSVEQVLVERTHQALEGAEDLLTDLLDISRLDQAAVKPDVALYRLDELFAPL
VSEFQSVALAAGLNLRARTGHYAIRTDLRLVTRILRNFLSNACRYTDDGCILLGARRRGD
CLRLEVWDTGRGIAADRLDAIFLEFNQLDVGRASDRKGVGLGLAIVERIAEILGYPVAVR
SWPGRGSMFSIEVPISEEMPLAISQLPVLPTTGNPLPGRRLLVIDNEVSILDSMRALLAQ
WGCEVITATDQAGALLALQGRAPELILADYHLDHGVVGCAVVKHLREHFAQNIPAVIITA
DRTDQCRRVLRRLDAPLLNKPLKPGKLRAVLSQLLT