Protein Info for GFF3400 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Lipoprotein releasing system ATP-binding protein LolD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 233 TIGR02211: lipoprotein releasing system, ATP-binding protein" amino acids 5 to 224 (220 residues), 370.3 bits, see alignment E=1.5e-115 PF00005: ABC_tran" amino acids 25 to 173 (149 residues), 133 bits, see alignment E=1.2e-42

Best Hits

Swiss-Prot: 100% identical to LOLD_SALTY: Lipoprotein-releasing system ATP-binding protein LolD (lolD) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K09810, lipoprotein-releasing system ATP-binding protein [EC: 3.6.3.-] (inferred from 100% identity to sec:SC1168)

MetaCyc: 95% identical to lipoprotein release complex - ATP binding subunit (Escherichia coli K-12 substr. MG1655)
RXN-22427

Predicted SEED Role

"Lipoprotein releasing system ATP-binding protein LolD"

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (233 amino acids)

>GFF3400 Lipoprotein releasing system ATP-binding protein LolD (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MNKILLQCDNLCKRYQEGTVQTDVLHDVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDT
PTSGDVIFSGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPA
EIDARAREMLHAVGLEHRATHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARN
ADSIFELLGELNRLQGTAFLVVTHDLQLAKRMSRQLEMRDGRLTAELSLMGAE