Protein Info for GFF3390 in Sphingobium sp. HT1-2

Annotation: Mercuric transport protein, MerT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 131 transmembrane" amino acids 23 to 55 (33 residues), see Phobius details amino acids 67 to 85 (19 residues), see Phobius details amino acids 108 to 128 (21 residues), see Phobius details PF02411: MerT" amino acids 17 to 131 (115 residues), 103.7 bits, see alignment E=3.2e-34

Best Hits

Swiss-Prot: 38% identical to MERT_ENTAG: Mercuric transport protein MerT (merT) from Enterobacter agglomerans

KEGG orthology group: K08363, mercuric ion transport protein (inferred from 65% identity to mmr:Mmar10_2327)

Predicted SEED Role

"Mercuric transport protein, MerT" in subsystem Mercury resistance operon

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (131 amino acids)

>GFF3390 Mercuric transport protein, MerT (Sphingobium sp. HT1-2)
MVSTPEAGQPALTENHEPKQANWVAAGALIGAGLASACCVVPLLLVMLGISGAWIANLTA
LEPYKPYVAGVTLALLGYGFWHVYFKPKPPCEDGSYCARPQSAWTTKAVLWLGLAVAILA
LTIDWWAPWFY