Protein Info for GFF3390 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Beta N-acetyl-glucosaminidase (EC 3.2.1.52)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00933: Glyco_hydro_3
  • amino acids 12 to 300 (289 residues), 364.3 bits, E=3.4e-113

Best Hits

Swiss-Prot: 100% identical to NAGZ_SALEP: Beta-hexosaminidase (nagZ) from Salmonella enteritidis PT4 (strain P125109)

KEGG orthology group: K01207, beta-N-acetylhexosaminidase [EC: 3.2.1.52] (inferred from 99% identity to stt:t1711)

MetaCyc: 92% identical to beta-N-acetylglucosaminidase (Escherichia coli K-12 substr. MG1655)
Beta-N-acetylhexosaminidase. [EC: 3.2.1.52]

Predicted SEED Role

"Beta N-acetyl-glucosaminidase (EC 3.2.1.52)" (EC 3.2.1.52)

MetaCyc Pathways

• peptidoglycan recycling I (14/14 steps found)
• peptidoglycan recycling II (7/10 steps found)
• chitin degradation II (Vibrio) (3/6 steps found)
• chitin degradation III (Serratia) (3/7 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Glycosaminoglycan degradation
• Glycosphingolipid biosynthesis - ganglio series
• Glycosphingolipid biosynthesis - globo series
• Nucleotide sugars metabolism
• Other glycan degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.52

Protein Sequence (341 amino acids)

>GFF3390 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
VGPVMLNVEGCELDAEEREILAHPLVGGLILFTRNYHDPEQLRELVRQIRAASRNHLVVA
VDQEGGRVQRFREGFTRLPAAQSFFALHGLEEGGRLAQEAGWLMASEMIAMDIDISFAPV
LDVGHISAAIGERSYHADPAKALAMATRFIDGMHDAGMKTTGKHFPGHGAVTADSHKETP
CDPRPETDIRGKDMSVFRTLISENKLDAIMPAHVIYRAIDPRPASGSPYWLKTVLRQELG
FDGVIFSDDLSMEGAAIMGSYAERAQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERV
TRLYHKGSFSRRELMDSARWKTASAQLNQLHERWQEEKAGH