Protein Info for PS417_01725 in Pseudomonas simiae WCS417

Annotation: sulfonate ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 transmembrane" amino acids 35 to 57 (23 residues), see Phobius details amino acids 62 to 83 (22 residues), see Phobius details amino acids 101 to 123 (23 residues), see Phobius details amino acids 135 to 158 (24 residues), see Phobius details amino acids 164 to 182 (19 residues), see Phobius details amino acids 201 to 222 (22 residues), see Phobius details amino acids 239 to 261 (23 residues), see Phobius details amino acids 273 to 294 (22 residues), see Phobius details amino acids 300 to 319 (20 residues), see Phobius details amino acids 331 to 352 (22 residues), see Phobius details amino acids 359 to 380 (22 residues), see Phobius details amino acids 401 to 420 (20 residues), see Phobius details amino acids 432 to 454 (23 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 21 to 443 (423 residues), 179.4 bits, see alignment E=5.8e-57

Best Hits

KEGG orthology group: K03457, nucleobase:cation symporter-1, NCS1 family (inferred from 97% identity to pfs:PFLU0362)

Predicted SEED Role

"Purine-cytosine permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TYR0 at UniProt or InterPro

Protein Sequence (485 amino acids)

>PS417_01725 sulfonate ABC transporter substrate-binding protein (Pseudomonas simiae WCS417)
MAANDARASTTPLIERRSIDYIPEAERHGRLFSQFTLWMGANLQITAIVTGALAVVLGGD
VFWSLIGLLVGQLIGGGVMALHAAQGPKLGLPQMISSRVQFGVYGAAIPIVLVCLMYLGF
TATGTVLSGQALGQLFGVSDSVGILIFASVIVLVTVLGYRVIHFIGRVASVIGVIAFVYL
FSRLMSQTDVGALLQIRHFSWSSFLLAVSLAASWQIAFGPYVADYSRYLPSNTSSLKTFL
AAGAGSVIGAQVAMILGVFAAAMSNGQFAGHEVAYIVGLSGTGATAALLYFSIAFGKVTI
STLNSYGSFMCIATIISGFRGRLEVTRLQRLVFVLAIVGTATLIALLGQHSFLGAFKSFI
LFLLAFFTPWSAINLVDYYCITRERYDVPALADPNGRYGRWNLLGISVYVFGVLVQLPFI
STKFYTGPLVAALGDVDISWIIGLVLPAALYYLCAKKWHGTVPDQLILPTEQGAIPRTNG
LAAQA