Protein Info for GFF3385 in Sphingobium sp. HT1-2

Annotation: Chromate transport protein ChrA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 transmembrane" amino acids 27 to 46 (20 residues), see Phobius details amino acids 95 to 116 (22 residues), see Phobius details amino acids 128 to 148 (21 residues), see Phobius details amino acids 160 to 188 (29 residues), see Phobius details amino acids 233 to 255 (23 residues), see Phobius details amino acids 267 to 287 (21 residues), see Phobius details amino acids 339 to 364 (26 residues), see Phobius details amino acids 376 to 400 (25 residues), see Phobius details amino acids 419 to 440 (22 residues), see Phobius details amino acids 446 to 464 (19 residues), see Phobius details PF02417: Chromate_transp" amino acids 25 to 187 (163 residues), 132.7 bits, see alignment E=7.1e-43 amino acids 264 to 458 (195 residues), 119.1 bits, see alignment E=1e-38 TIGR00937: chromate efflux transporter" amino acids 29 to 408 (380 residues), 217.2 bits, see alignment E=2.6e-68

Best Hits

KEGG orthology group: K07240, chromate transporter (inferred from 77% identity to sjp:SJA_C1-21240)

Predicted SEED Role

"Chromate transport protein ChrA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (465 amino acids)

>GFF3385 Chromate transport protein ChrA (Sphingobium sp. HT1-2)
MEASARAEIAVETLHEHGISFGEAVRVWIRVALLSFGGPAGQIAVMHRILVEEKRWIGEE
RFLHALNYCMLLPGPEAQQLAVYIGWLLHKTKGGLVAGALFVLPGFLAILGLSYVYVLLG
EVPLVEGLFFGLKAAVLAVVLQAVVRVGSRALKNNVMRGFAALAFVAIFVLDVPFPLIVL
AAALIGFFSGRAGYAAFKGGGGHGPAGAEIIHDRDTALGEGLPDHARPNLSWSLRISGVL
LLLWLGPVAALLFAFGPDDVFSRIATFFSQMAVMTFGGAYAVLAYVAQEAVETYGWLQPG
EMLDGLGMAETTPGPLIMVTQFVGFLAAFREATGLPPLVAATFGAILTTWVTFLPCFLWI
FAGAPFIERLRGNRALSAALSAITAAVVGVILNLAVWFGIHTLFEQVREVPFAAGTIDLP
VLTSVNWPALALAVGAILAMFRFKAGMLPVLGVCSVLGAAYVMII