Protein Info for PS417_17290 in Pseudomonas simiae WCS417

Annotation: RND transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1073 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 335 to 354 (20 residues), see Phobius details amino acids 361 to 381 (21 residues), see Phobius details amino acids 387 to 408 (22 residues), see Phobius details amino acids 429 to 453 (25 residues), see Phobius details amino acids 463 to 483 (21 residues), see Phobius details amino acids 560 to 578 (19 residues), see Phobius details amino acids 902 to 924 (23 residues), see Phobius details amino acids 931 to 950 (20 residues), see Phobius details amino acids 957 to 981 (25 residues), see Phobius details amino acids 1002 to 1022 (21 residues), see Phobius details amino acids 1034 to 1056 (23 residues), see Phobius details PF00873: ACR_tran" amino acids 5 to 1057 (1053 residues), 671.3 bits, see alignment E=2.4e-205 PF03176: MMPL" amino acids 870 to 1059 (190 residues), 25.1 bits, see alignment E=8.5e-10

Best Hits

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U0Y3 at UniProt or InterPro

Protein Sequence (1073 amino acids)

>PS417_17290 RND transporter (Pseudomonas simiae WCS417)
MLGLVKTALQKPYTFIVLAIFICIIGPMAALRTPTDVFPDIGIPVVAVVWQYNGLSPDAM
AGRVIYTYERSLSTTVNDIEHIESQSLPGMGIVKIFFQPGVDIRTANAQVTAVSQTVLKQ
MPPGITPPLILNYSASTVPILQMAFSSPSLSEAKIRDLVQNNIRLPLSALPGLAMPTPMG
GKQRQITLDLDPQALAAKGLSAQDVGNALALQNQIIPVGTAKLGPNEYTILLNNSPKAID
ELNDLPIKTVDGALITIGQVAHVRDGSPPQTNIVRVDGHRAVLMPALKNGSISTLSIIDG
IRQMLPRINETLPPSLKTSLLGDASVFVKQSVGSVAQEGIIAALLTSAMILLFLGSWRST
IIIAASIPLAVLSAIALLAVSGQTLNVMTLGGLALAVGILVDDATVTIENINWHLEQGKA
VKTAILDGAAQIVGPAFVSLLCICIVFVPMFLLQGIAGYLFRPMALAVIFAMASSFILSR
TLVPTLAMFLLKPHVPEQGAGHHPEDEFINHHEGEQHTQQRNAVLQGVLNFQQGFERHFS
NIRDTYHGLLTLALGNRKRFIVGFLACVLASFLLLPSLGQDFFPATDAGALALHVRLPLG
TRIEESAAAFDRIEARIREVIPAEELDTIVDNIGIPLSGIDMAYSSSGTIGPQDGDIQVT
LKKDHAPTADYVKKLREALPQSFPGSHFAFLPADISSQILNFGAPAPLDVKISGRSDEEN
RAYAVELERRLQHVPGIADLRIQQSTGYPSLQVNVDRLRANGLGITERDVTNSMVASLAG
SSQVAPTFWLNPANGVSYSIVAATPQYRLDSLPSLEALPVTGAGGQSQILGGVASISRVE
SPAVVTHYNIEPTLDLYANVQGRDLGGVARDVQKVLDDTAAMRPKGAVISLHGQIDALHE
AFSGLSFGLLGAVVLIYLLIVVNFQSWADPFVIITALPAALAGIVWMLFLSGTSLSVPAL
TGAILCMGVATANSILVVSFCRERLAEHGDALKAAMEAGYTRFRPVCMTALAMIIGMLPL
AISEEQNAPLGRAVIGGLIFATIATLLFVPVVFSLIHGRHPTRAVAGETPHVV