Protein Info for GFF3358 in Sphingobium sp. HT1-2

Annotation: Carbon monoxide oxidation accessory protein CoxG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 223 transmembrane" amino acids 173 to 190 (18 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details PF10604: Polyketide_cyc2" amino acids 3 to 141 (139 residues), 32 bits, see alignment E=2.2e-11 PF06240: COXG" amino acids 5 to 144 (140 residues), 122.7 bits, see alignment E=1.5e-39 PF03364: Polyketide_cyc" amino acids 9 to 113 (105 residues), 29 bits, see alignment E=1.7e-10

Best Hits

KEGG orthology group: K09386, hypothetical protein (inferred from 49% identity to pgv:SL003B_3009)

Predicted SEED Role

"carbon monoxide dehydrogenase G protein" in subsystem CO Dehydrogenase or Carbon monoxide dehydrogenase maturation factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (223 amino acids)

>GFF3358 Carbon monoxide oxidation accessory protein CoxG (Sphingobium sp. HT1-2)
MRMTGEERIAAPRDAVWQALNDPAVLRQCIPGCQSLERDGEDRLRAEIAVKIGPIGARFA
GTVTLSEIDAPNGYRISGEGQGGTVGHARGGAKVTLADGGLATRLSYAVEAEVGGRLAQL
GGPIIDATAKQLAGQFFRNFNAVVSGVGVPTEGAPVAAAPAPVQAPPSAGGHPWGWIIAL
LLALATGVLLERSGVAGTGMVAIGLLLAVTALAGFEAGRRGRR