Protein Info for GFF3341 in Xanthobacter sp. DMC5

Annotation: Pyruvate dehydrogenase complex repressor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 transmembrane" amino acids 184 to 201 (18 residues), see Phobius details PF00392: GntR" amino acids 24 to 88 (65 residues), 75.5 bits, see alignment E=3.1e-25 PF13545: HTH_Crp_2" amino acids 47 to 80 (34 residues), 27.1 bits, see alignment 5e-10 PF07729: FCD" amino acids 117 to 234 (118 residues), 81.8 bits, see alignment E=8.5e-27

Best Hits

KEGG orthology group: None (inferred from 89% identity to xau:Xaut_3347)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (256 amino acids)

>GFF3341 Pyruvate dehydrogenase complex repressor (Xanthobacter sp. DMC5)
MTTGVPGTDQMEPSYGQIVTTSAASQIADQLQQAIMDGRLKVDERLPTEEELAAQFGVSR
PTVREALKRLAARHLIRSRRGPTGGTFVTGPSPEELATSLGTSVTLLVATGGVSLEEMAT
ARLEMEAVCCRLAALNRTEAHLSALEAEIALQRTASLSDQDFCASDVRFHRTIVDAAGNA
LLRFLMNAVVEALMPVSNMIIFRVRDRKEIVAHHETLLAALRDRDGEAAVAALGGLVRYI
RAQYEKAEEARKAARP