Protein Info for GFF3330 in Sphingobium sp. HT1-2

Annotation: Cell division protein BolA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 95 PF01722: BolA" amino acids 17 to 94 (78 residues), 99.7 bits, see alignment E=4.7e-33

Best Hits

Swiss-Prot: 49% identical to YCB1_SINSX: Uncharacterized protein in cobS 5'region from Sinorhizobium sp.

KEGG orthology group: K05527, BolA protein (inferred from 90% identity to sch:Sphch_2357)

Predicted SEED Role

"Cell division protein BolA" in subsystem Bacterial Cell Division

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (95 amino acids)

>GFF3330 Cell division protein BolA (Sphingobium sp. HT1-2)
MTTDLKGPVATEIEARLRAALTPAHLAVIDDSEKHRGHAGHDGSGESHFTVEIVAERFVG
QSRVARQRLVNAALADLLRDKVHALAIKARAPGEV