Protein Info for GFF3311 in Sphingobium sp. HT1-2

Annotation: Homoserine/homoserine lactone efflux protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 206 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details amino acids 39 to 65 (27 residues), see Phobius details amino acids 74 to 91 (18 residues), see Phobius details amino acids 111 to 138 (28 residues), see Phobius details amino acids 144 to 165 (22 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details PF01810: LysE" amino acids 16 to 202 (187 residues), 136.8 bits, see alignment E=3.3e-44

Best Hits

Swiss-Prot: 36% identical to RHTB_ECOLI: Homoserine/homoserine lactone efflux protein (rhtB) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 85% identity to sjp:SJA_C1-34540)

MetaCyc: 36% identical to L-homoserine/L-homoserine lactone/L-threonine exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-242; TRANS-RXN-242A; TRANS-RXN0-0244

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (206 amino acids)

>GFF3311 Homoserine/homoserine lactone efflux protein (Sphingobium sp. HT1-2)
MSLHLWWLYVTAVFLISATPGPNMLHVMTQSIAHGPRKALVTMAGLMSAVLLCLIASALG
LGALLKASPRLFDILRYAGVAYLIWLGIKAWRAPVGTADGGDAGPVRSARALYATGLLTG
LSNPKLIIFAAALFPQFIDLGRPFWLQLAILIVSFVVIESFWYSVYALGGLRLARWLAPA
NRQKLFNRGTGLMFIGFGGALLGARA