Protein Info for GFF3308 in Variovorax sp. SCN45

Annotation: Inner membrane protein CreD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 487 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 347 to 365 (19 residues), see Phobius details amino acids 373 to 392 (20 residues), see Phobius details amino acids 398 to 420 (23 residues), see Phobius details amino acids 428 to 445 (18 residues), see Phobius details amino acids 451 to 470 (20 residues), see Phobius details PF06123: CreD" amino acids 12 to 476 (465 residues), 423 bits, see alignment E=6.9e-131

Best Hits

KEGG orthology group: K06143, inner membrane protein (inferred from 86% identity to vpe:Varpa_0024)

Predicted SEED Role

"Inner membrane protein CreD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (487 amino acids)

>GFF3308 Inner membrane protein CreD (Variovorax sp. SCN45)
MLQLLKALQSSMLVKVAGLFFLLLLLCIPLAEIDSINRERGESQREAARELAATYAGRQT
VVGPLLLVPYVERWMEPLRNAQGKVIGQEPRSKEMAHVVFPDKLHIEGTMAPQERYRGIF
RIPFYTLNATLGGGFAAFDPKAVSHSETDSKIEFKAPFIAFNVSDLRGLDGSPAMVMGGE
ALRFRQRVPGLADDAWFADGIHAPVTGAALAAWQAGTPVAFEMKIGLVGQDTLAIAPIAE
ETTAHLTSPWAHPSFGGRFLAAERSVTPQGFDAHWRVSSLVTSAREQVRSGLSGRGGPAD
GDTADVVSANATTANAPRRNMGPLQTFDVSLAQPINVYSMSTRAGKYGALFIGLVLMAAF
MFELFRKLRLHPIQYGLVGLSIALFFLLLLALSEKFAFWMAYAGAATASVVLLAVYFSAV
LEGWRRGLSFGAFVALLYGALYGLLASESNALLLGALLIFGMLAVLMLVTRKVDWYALSR
RTDNAPA